Lung – Lung Cancer

There are two types of lung cancer: non-small cell lung cancer and small cell lung cancer. Smoking causes most lung cancers, but non-smokers also get lung cancer.

Lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Signs and symptoms of lung cancer include coughing and shortness of breath.

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Oncothermia to Slow Down the Progression and Prevent the Development of Ultimate Pulmonary Fibrosis by COVID-19

Oncothermia to Slow Down the Progression and Prevent the Development of Ultimate Pulmonary Fibrosis by COVID-19

Right now, we are facing a global pandemic caused by the coronavirus SARS-CoV-2 that causes the highly contagious human disease COVID-19. The number of COVID-19 cases is increasing at an alarming rate, more and more people suffer from it, and the death toll is on the rise since December 2019, when COVID-19 has presumably appeared.

We need an urgent solution for the prevention, treatment, and recovery of the involved patients.

Methods

Oncothermia (Modulated electro-hyperthermia, mEHT) is known as an immuno-supportive therapy in oncology. The proposal from a group of scientists from the McGill University, Canada, is to apply this method to prevent the progression of the Pulmonary Fibrosis after its identification, to provide treatment when necessary, and deliver rehabilitation to diminish the fibrotic—often fatal—consequences of the infection.

Hypothesis

The effects of Oncothermia, which are proven for oncological applications, could be utilized for the inactivation of the virus or for treating the fibrotic consequences.

In the other hand, the hypothesized Oncothermia effects, which could have a role in the antiviral treatment, it could be applied for viral-specific immune-activation and for anti-fibrotic treatments.

It´´` is remarcable, that the proposal focuses on the electromagnetic impact, which combines the effects caused by heat and electric field, using their strong synergy. Temperature-dependent and non-temperature dependent factors are combined for optimal treatment. Oncothermia uses the biophysical differences between the malignant and healthy cells to select them and induce apoptotic signals; and immune-mediated abscopal effect.

These method has a long and successful history; it is applied in oncology all over the world.

Radiofrequency current flows into the direction of the lower impedance. (A) The increased metabolic activity of the infected cells allow lower impedance (higher conductance) in their microenvironment than in the healthy cells. (B) The electric field selects the volumes with a high concentration of the infected cells. (C) the lung-lesions are loaded more with the radiofrequency current than the non-infected parts.

The thermal aggregation of the SARS-CoV membrane protein may be one of the reasons for the inactivation of this virus by heat. The Oncothermia is also a partly thermal method, which locally heats the membrane rafts of the targeted cells in-depth.

Antiviral immune-effect of Oncothermia: the Oncothermia selects the infected cells which release a damage-associated molecular pattern through the process of immunogenic cell-death. The DAMP provides viral genetic information to maturate the dendritic cells producing antigen presentation for T-cells, which turn to viral specific CD4+ CD8+ form. Viral-specific T-cells attack the infected cells in all over the body.

More Information

For more information, you can consult the following link.

If you want more information regarding Oncotermia applied to cancers, you can visit the following link.

International Lungcancer Symposium

International Lungcancer Symposium

Oncothermia is an adjuvant method for the treatment of cancers, as in the case of Lung Cancer. It stands out for being a non-invasive method that can be combined with radiotherapy and chemotherapy.

Oncothermia is present internationally in congresses and conferences. In these scientific meetings doctors make presentations to disseminate the results of clinical cases.

2nd International Symposium on lung cancer

On April 17, 2016, in Budapest, the 2nd International Symposium on Lung Cancer took place (2nd International Lungcancer Symposium). The conference was organized in different sections. Professor Szasz directed the section: “Oncothermia in Advanced Lung Cancer”, where he presented his latest research and clinical results.

Oncothermia in combination with Radiotherapy exerts a radiosensitizing effect in lung cancer.

efecto radiosensibilizante en el Cáncer de PulmónOncothermia in combination with Radiotherapy exerts a radiosensitizing effect in lung cancer.

The sensitivity of tumors to radiotherapy and chemotherapy is increased by Oncothermia.

Oncothermia, also known as electro-hyperthermia, is a new treatment modality that allows for increased sensitivity to other treatments. It has been developed to overcome the problems of traditional hyperthermia by targeting malignant tissues.

A study was published in 2015 in the journal Experimental and Therapeutic Medicine. It reports the outcome of combined oncothermia and RT in a 75-year-old patient with stage IIIB non-small-cell lung cancer (NSCLC).

Due to the advanced age and the performance status of the patient, the combination of systemic chemotherapy and RT was deemed infeasible. Therefore, the patient instead decided to undergo oncothermia concurrently with definitive RT.

The RT was administered at a dose of 64.8 Gy in 36 fractions using a three-dimensional conformal plan technique. In this case, Oncothermia was started concomitantly with RT. And was performed for 60 min per session, two sessions per week, for a total of 12 sessions.

Follow-up computed tomography showed complete tumor response. And the patient was alive with no evidence of the disease 18 months after the completion of the treatment.

In conclusion, the present case report suggests that oncothermia combined with RT has former possessing radiosensitizing potential and no additional toxicities. May be it is a promising alternative for advanced-age and/or frail patients with locally advanced NSCLC.

In addition, you can find more information about lung cancer on our website.

Stage IV Kidney Cancer treated by Oncothermia and herbs

Stage IV Kidney Cancer (Wilms Tumor) treated by Oncothermia and herbs

[message_box title=”Wilms tumour is the most common cause of kidney cancer in childhood and adolescence.” color=”red”]It also carries a mortality rate of 7-8 in one million. The 5-year survival rate for kidney cancer is 77.2 – 87.5%. When Wilms tumour progresses, radiotherapy and chemotherapy are conventionally used as the only treatments.[/message_box]

Clinical case

A 17-year-old Korean woman was treated from October 25, 2014, until July 22, 2015 with an integrating medical treatment, in order to control the extent of her illness.

The integrative medical treatment included: oncothermia, thymosin-α1 and phytotherapy. Phytotherapy was administered in 8 ml. of inhalation of Soram nebulizer solution qd, Soramdan S 8 g po, Hangamdan S 1 g po, tid, Cheongjangtang 10-30 ml, and Spiam HC 8 g po. She received Oncothermia (2-3 times a week) and 1.6 mg of treatment with thymosin-α1 (Zadaxin) i.m.

Result

According to the result of the CT on July 15, 2015, the liver metastasis was no longer seen, while the lung metastasis remained stable without tumor progression.

Conclusion

In patterns of Wilms tumor progression after surgery and chemotherapy, integrative medical treatment can be significant for disease control.

Reference

Lee D, Kim SS, Seong S, Cho W, Yu H. Stage IV Wilms Tumor Treated by Korean Medicine, Hyperthermia and Thymosin-α1: A Case Report. Case Rep Oncol. 2016 Feb 20;9(1):119-25. doi: 10.1159/000443724. 

If you wish, you can find more information about clinical cases treated with Oncotermia on our website.